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Evaluation of Responses to Vaccination of Angus Cattle for Four Viruses that Contribute to Bovine Respiratory Disease Complex

机译:评价对四种牛源性呼吸道疾病综合症病毒对安格斯牛的疫苗接种反应

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摘要

Initial antibody titers are maternally-derived from colostrum, then decay with age. Change in antibody titer levels were compared between four viruses contributing to the Bovine Respiratory Disease Complex (BRDC), and evaluation of response to vaccination indicated that antibody production will not occur when high levels of maternal antibodies are present. The maternal antibodies were found to decay with calf age for each of the four viruses, which allowed for the estimation of a maximum circulating titer level under which a positive antibody response to vaccination could occur. Phenotypic correlations were calculated between the antibody titers for the four viruses across multiple time points. Results indicate a difference in the response to vaccination between the four virus antigens
机译:最初的抗体效价是母源于初乳,然后随着年龄的增长而衰减。比较了造成牛呼吸道疾病综合症(BRDC)的四种病毒之间抗体效价水平的变化,对疫苗接种反应的评估表明,如果存在高水平的母源抗体,则不会产生抗体。对于四种病毒中的每一种,发现母体抗体都随着牛的年龄而衰减,这使得可以估计最大循环效价水平,在该水平下可能会出现针对疫苗的阳性抗体反应。计算了跨多个时间点的四种病毒的抗体效价之间的表型相关性。结果表明四种病毒抗原对疫苗接种反应的差异

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